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Global Specialty Enzymes Market - Outlook and Forecast 2022-2027
The global specialty enzymes market surpassed USD 2.96 billion in 2021 and is projected to reach USD 4.56 billion by 2027, growing at a CAGR of 7.46% during the forecast period of 2021-2027. This growth can be attributed to several factors, including the increasing global population, rising research and development activities, the emergence of new infectious diseases, the growing use of biofuels, and the expanding agriculture industry. Furthermore, the specialty enzymes market is driven by the rising health consciousness and the extensive penetration of the pharmaceutical, diagnostics, and biotechnology industries.
Specialty enzymes find applications across various industries for different purposes. In the pharmaceutical sector, they are utilized in the production of drugs for DNA/RNA treatment, cancer, cardiovascular diseases, and other medical conditions. The demand for specialty enzymes in this sector is increasing due to rising awareness and evolving government regulations. As the specialty enzymes market expands, companies need to ensure a sufficient supply of raw materials to produce enzymes in large quantities. In the pharmaceutical industry, there is also a growing trend toward using biobased drugs to enhance product quality. Moreover, companies are adopting sustainable practices in their manufacturing processes, leading to reduced by-products. The incorporation of specialty enzymes in production processes has proved financially beneficial for these companies. Consequently, the global demand for specialty enzymes continues to rise.
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USD 3 billion in 2020
Type, End Use, Source, and Geography
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North America, particularly the United States, contributes the largest share to the specialty enzymes market in North America. This region dominates the global specialty enzymes market, given that the United States is home to the headquarters of several top pharmaceutical companies worldwide. Thus, the demand for specialty enzymes in North America’s pharmaceutical industry is consistently increasing alongside the sector’s overall growth.
The diagnostics industry comprises pathology and radiology. Pathology involves the testing of various illnesses, while radiology focuses on diagnostic imaging techniques such as x-rays and CT scans. Enzymes play a crucial role in the research and development of vaccines for various infectious diseases. They are also employed for testing infectious diseases like coronaviruses and influenza, as well as nucleic acid detection. Enzymes are essential in the diagnostics and analysis of biological abnormalities.
The diagnostics sector plays a vital role in the healthcare industry, and its demand for accurate diagnostic equipment and processes has surged following the Covid-19 pandemic. Enzymes are extensively used in the testing of coronaviruses and other infectious diseases. Additionally, enzymes contribute to the production of antibiotics, which aid in the rapid recovery from coronavirus infections. Thus, the specialty enzymes market within the diagnostics sector is experiencing significant growth on a global scale.
The global pharmaceutical industry is witnessing a rise in revenue due to the growing demand for pharmaceutical products. Factors driving this demand include changes in clinical practices, demographic aging issues, and the increasing prevalence of chronic diseases. The Covid-19 pandemic further accelerated the demand for pharmaceutical products that improve quality of life and adopt a preventive approach. In the United States, the lowering of regulatory barriers for new drugs has contributed to the global market expansion of pharmaceutical products.
Following the Covid-19 pandemic, people have become more health-conscious and exhibit a preference for bio-based pharmaceutical products. Consequently, the demand for bio-based substances used in antibiotic manufacturing has increased. Specialty enzymes play a pivotal role in the pharmaceutical industry by accelerating reaction rates and facilitating the production of desired molecules, thereby driving growth in the specialty enzymes market.
Biocatalysis refers to a process that utilizes biomolecules to accelerate chemical reactions, offering mild reaction conditions and high selectivity. Specialty enzymes have significant relevance in the chemical industry and are increasingly applied in industrial applications. However, accurately determining the protein structure of specialty enzymes poses challenges and is a time-consuming process. Additionally, a larger number of catalysts are needed to fulfill the requirements of chemical reaction processes. The manufacturing of these enzymes necessitates specific conditions such as precise concentrations and substrates, which are not readily available in nature. These unresolved challenges lead to unpredictability in the specialty enzymes market. Therefore, further research and development are crucial for enabling large-scale production of enzymes, acting as a barrier to the growth of the specialty enzymes market.
The market is segmented based on various factors, including type, end use, source, and geography.
Segmentation by Type
Polymerases & nucleases
Segmentation by End Use
Segmentation by Source
Segmentation by Geography
North America – US, Canada
Europe – Germany, France, UK, Italy, Spain, Russia, Rest of Europe
APAC – China, Japan, India, South Korea, Rest of APAC
Latin America – Brazil, Mexico, Rest of Latin America
Middle East & Africa – South Africa, Saudi Arabia, Rest of MEA
Specialty enzymes play a crucial role in the pharmaceutical industry, where they are used for the treatment of various diseases. With the growing demand for pharmaceutical products, specialty enzymes have become essential in meeting the industry’s need for sustainable and safe processes. These enzymes find primary applications in pharmaceutical research and development as well as diagnostics. In 2021, the global specialty enzymes market in the pharmaceutical industry was valued at USD 976.56 million, with a particularly high demand in North America and the Asia-Pacific (APAC) region driven by the flourishing pharmaceutical and biotechnology sectors.
In the biotechnology industry, specialty enzymes are employed to enhance biochemical reaction rates. Lipases, for example, are utilized in dietary drugs to boost metabolism. Polymerases and nucleases, on the other hand, are instrumental in DNA amplification, a process that leads to an increase in gene numbers, protein production, and RNA synthesis. Consequently, this amplification may either promote the growth of cancer cells or hinder anticancer cells. As a result, the demand for polymerases and nucleases-based enzymes is growing in the global specialty enzymes market.
Carbohydrases have dominated the global specialty enzymes market and are projected to reach USD 1.9 billion by 2027. These enzymes find extensive use in the pharmaceutical industry, with a majority of them being derived from microorganisms, animals, and plants. Carbohydrases are further categorized into different types such as glucosidase, pectinases, alpha and beta amylases, cellulases, mannanases, galacto- and pullulanase. Though these processes are cost-effective in industrial applications, efforts are needed to develop more affordable techniques.
In 2021, the global specialty enzymes market for proteases surpassed USD 813 million. Proteases are widely applied in the biotechnology, pharmaceutical, and diagnostics industries, particularly in the pharmaceutical field for prognostic and diagnostic biomarkers. Proteases can be classified into various classes based on their catalysis mechanism, including glutamic, aspartic, metalloproteases, threonine, cysteine, and serine proteases, each with unique characteristics such as activation of water molecules and protein degradation.
Microorganisms-based enzymes contributed 77.47% to the global specialty enzymes market in 2021, followed by animal and plant-based enzymes. Microorganisms and plant-based enzymes are readily available in the environment, whereas animal-based enzymes face limitations in terms of resources and large-scale production. Consequently, companies are focusing on producing enzymes from microorganisms and plants.
The global market for plant-based specialty enzymes was valued at USD 297.07 million in 2021. These enzymes find applications in the agriculture industry for insect reduction in crops. They include enzymes such as phosphatase, esterase, glucanase, chitinase, and others, which play a crucial role in improving nutrition production. Additionally, plant-based enzymes are utilized in the pharmaceutical industry to manufacture drugs that aid in improving the digestive system.
The global specialty enzymes market is diverse, encompassing both established and potential growth markets. North America leads the market, driven by the region’s rapidly developing infrastructure and increasing population, resulting in heightened demand for pharmaceutical, biotechnology, and diagnostics industries. In 2021, the specialty enzymes market in North America reached a value of USD 1.2 billion.
Europe stands as the second-largest market for specialty enzymes, with the growing demand for healthy pharmaceutical products due to rising health consciousness. Countries such as Germany, France, Italy, Spain, the UK, and Russia are key contributors in this region, with companies like BASF SE (Germany), Johnson Matthey (UK), Biocatalysts (UK), BBI Solutions (UK), among others, actively participating in the global specialty enzymes market. Furthermore, the APAC region is expected to experience significant growth due to its rapidly increasing population. Countries like China, Japan, India, and South Korea are leading in this region, with China, India, and Japan being major players in the pharmaceutical industry.
The leading companies in the specialty enzymes market are employing a merger and acquisition strategy to gain a competitive advantage and increase their market share. These key players have implemented various strategies to foster growth in the market. The industry-wide focus on sustainable processes and initiatives presents challenges and opportunities for all companies globally. The demand for innovative and sustainable specialty enzyme products is driven by investments in research and development, technological advancements, as well as environmental and economic concerns.
Prominent players in the global specialty enzymes market include Roche (Switzerland), BASF SE (Germany), DuPont (US), Novozymes (Denmark), and DSM (Netherlands). These companies have adopted strategies such as acquisitions, expansions, joint ventures, and new product development to enhance their revenue in the industry. Other notable companies like Chr. Hansen Holding A/S (Denmark), Codexis (US), BBI Solutions (UK), and others have also made significant investments in research and development to develop specialty enzyme-based products that cater to customer demands. As a result, these other prominent companies pose strong competition to the major players.
Key companies profiled in this report include BASF SE, DSM, DuPont, F. Hoffmann-La Roche Ltd, Novozymes, Amano Enzyme Inc., Product Offerings, Amayra Biotech AG, Antozyme Biotech Pvt Ltd, Aumgene Biosciences, Aumenzymes, BBI Solutions, Biocatalysts, Codexis, Hansen Holding A/S, Dyadic International Inc., Iosynth, Merck KGaA, Nature Bioscience Pvt. Ltd., Specialty Enzymes & Probiotics, Zymtronix Inc.
Key Questions Answered
What was the global market size of specialty enzymes in 2021?
The global market size of specialty enzymes exceeded USD 2.96 billion in 2021 and is projected to reach USD 4.56 billion by 2027.
What is the growth rate of the global specialty enzymes market?
The global specialty enzymes market is experiencing a compound annual growth rate (CAGR) of 7.46% from 2021 to 2027.
What are the key trends in the global specialty enzymes market?
Some key trends in the global specialty enzymes market include the increasing demand from the pharmaceutical industry, the adoption of sustainability standards to enhance profitability and productivity, and the growing demand from emerging economies.
Which companies are considered key players in the global specialty enzymes market?
BASF SE, DSM, DuPont, F. Hoffmann-La Roche Ltd, and Novozymes are among the key companies in the global specialty enzymes market.
Which end-use segment is expected to lead the global specialty enzymes market?
The pharmaceutical industry is estimated to dominate the global specialty enzymes market in terms of end-use, with a projected value of USD 1.4 billion by 2027. The increasing global population and rising health consciousness among individuals have led to a growing demand for pharmaceutical products. Consequently, pharmaceutical companies are focusing on incorporating more bio-based drug content in their formulations.