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Market Overview

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The global market for single-use bioprocessing probes and sensors reached a value of USD 1 billion in 2021 and is projected to reach USD 2.6 billion by 2027, with a compound annual growth rate (CAGR) of 16.32%. These probes and sensors offer an effective alternative to traditional methods in biopharmaceutical development and manufacturing, particularly in support of continuous bioprocessing.

Unlike conventional bioreactors and fermenters made of stainless steel or glass, single-use bioreactors and fermenters consist of disposable plastic bags installed into outer metal containers. The increasing adoption of single-use technologies in the biopharmaceutical industry for the production of biologics, vaccines, and cell therapies indicates that this technology has moved beyond its novelty stage.

The demand for single-use bioprocessing probes and sensors is driven by the rise of bioprocessing in biopharmaceutical manufacturing and the advantages offered by single-use systems. Single-use equipment allows for pre-sterilization before use, eliminates the need for classified environments, reduces the risk of cross-contamination, and leads to lower costs, increased efficiency, and greater flexibility.

To meet the growing demand, vendors are focusing on developing advanced products that meet current requirements. Non-invasive probes and sensors that minimize the risk of cross-contamination have been introduced, along with smart single-use probes and sensors that incorporate memory devices for recording calibration data and carrying sensor-specific information.

The COVID-19 pandemic has further boosted the demand for single-use bioprocessing probes and sensors, driven by the need for COVID-19 vaccines, cell and gene therapies, and monoclonal antibody manufacturing. The vaccine segment is expected to exhibit the highest CAGR of 16.99% due to the increased demand for vaccine development in various therapeutic areas, particularly during the pandemic.

Overall, the single-use bioprocessing probes and sensors market is experiencing significant growth and offers promising opportunities for stakeholders involved in the biopharmaceutical industry.

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Market Segmentation

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The market is segmented based on various factors, including type of sensors, workflow, application, end-user, and region.

Segmentation by Type of Sensors
pH
Oxygen
Pressure
Temperature
Flow Meters & Sensor
Other

Segmentation by Workflow
Upstream
Downstream

Segmentation by Application
Monoclonal Antibody
Vaccines
Cell Therapies
Others

Segmentation by End-User
Biopharmaceutical Manufacturers
CMOS & CDMOS
R&D Companies & Institutes

Segmentation by Geography
North America – US, Canada
Europe – Germany, France, UK, Italy, Spain, Switzerland
APAC – China, Japan, India, South Korea, Australia, Colombia
Latin America – Brazil, Mexico, Argentina
Middle East & Africa – South Africa, Saudi Arabia, Turkey, UAE

Contract manufacturing organizations (CMOs) play a crucial role in the biopharmaceutical industry and contribute significantly to creating valuable investments. Companies with substantial financial resources, strong reputations, and a willingness to take risks are well-positioned to lead the market. CMOs that have achieved the necessary scale and possess specialized operations dominate the market, offering the potential for high economic returns.

The widespread adoption of single-use bioreactors by CMOs has led to an increased demand for single-use probes and sensors in recent years. This is because CMOs prefer the higher flexibility provided by single-use manufacturing, which allows for time and cost savings. Currently, around 60% of CMOs utilize single-use probes and sensors for bioreactors in the production of biologics. Consequently, the growing demand for single-use probes and sensors is fueled by the increasing growth and manufacturing of biopharmaceuticals.

CMOs have been among the earliest adopters of single-use bioprocessing probes and sensors, with over 30% of bio manufacturers and 39% of CMOs expressing interest in these products for new product development.

Among the various types of single-use bioprocessing probes and sensors, pH sensors are the most commonly used in the industry. These pH sensors enable improved equipment inventory control for both process device manufacturers and end-user sites. As a result, pH sensors hold the largest market share, accounting for 23.23% among other sensor types.

The upstream segment dominates the market for single-use bioprocessing probes and sensors, generating the highest revenue of $4,712.96 million in 2021. The widespread adoption of single-use bioreactors for upstream bioprocessing has significantly driven the usage of single-use probes and sensors.

In contrast, the downstream processing, particularly the affinity capture step and purification, is more intensive and costly. The lower penetration of single-use systems in downstream processing has resulted in a smaller market revenue share for this segment. Nevertheless, industry players are actively working to expand the utilization of single-use systems in the downstream process, and this segment is expected to experience significant growth during the forecast period.

The increasing investment in research and development for biopharmaceutical products contributes to the high adoption of single-use bioreactors, subsequently driving the growth of the single-use bioprocessing probes and sensors market. This demand is particularly evident in North America and Europe. North America generated the highest revenue in 2021, amounting to $409.58 million, with numerous companies holding strong positions in the region. Collaborations between original equipment manufacturers and independent suppliers also contribute to market growth. Key players such as Avantor, High Purity New England, and Merck play vital roles in the expansion of the single-use bioprocessing sensors market in the United States, supported by increased investments from large companies to expand their single-use bioprocessing facilities.

The growing demand and expanding usage of single-use bioreactors in North America and Europe are major drivers of market growth in these regions. Furthermore, North America and Europe are leading other regions in terms of investment for the development and distribution of advanced products.

In recent years, there has been a notable increase in the expansion of manufacturing facilities for single-use bioprocessing in several countries across Latin America, the Middle East, and Africa. This presents significant opportunities for market growth.

The emphasis on research activities and high R&D spending in the Asia-Pacific (APAC) region has led to an increased adoption of single-use bioprocessing technologies for biopharmaceutical manufacturing, resulting in the growth of the APAC single-use bioprocessing probes and sensors market with a projected CAGR of 17.86%.

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Competitive Landscape

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The global market for single-use bioprocessing is characterized by moderate competitiveness and presents substantial growth prospects for vendors. Thermo Fisher Scientific, Sartorius, Danaher, and Merck are among the prominent companies that hold a dominant position in this market.

Key companies profiled in this report include Thermo Fisher Scientific, Sartorius, Danaher, Merck KGAA, Aber Instruments, Avantor, Broadley-James, CerCell, Cole-Parmer Instrument Company, Distek, Emerson Electric, ESI Technologies Group, Hamilton Company, High Purity New England, Levitronix, Liquidyne Process Technologies, Malema Engineering, METTLER TOLEDO, PARKER HANNIFIN, PreSens Precision Sensing, PSG, Saint-Gobain, SONOTEC.

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Key Questions Answered

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HOW LARGE IS THE GLOBAL MARKET FOR SINGLE-USE BIOPROCESSING PROBES AND SENSORS?

The global market for single-use bioprocessing probes and sensors was valued at USD 1 billion in 2021 and is projected to reach USD 2.6 billion by 2027.

WHAT IS THE GROWTH RATE OF THE GLOBAL MARKET FOR SINGLE-USE BIOPROCESSING PROBES AND SENSORS?

The global market for single-use bioprocessing probes and sensors is expected to grow at a compound annual growth rate (CAGR) of 16.32% during the period from 2022 to 2027.

WHO ARE THE KEY PLAYERS IN THE GLOBAL MARKET FOR SINGLE-USE BIOPROCESSING PROBES AND SENSORS?

The key players in the global market for single-use bioprocessing probes and sensors include Thermo Fisher Scientific, Sartorius, Danaher, and Merck KGAA.

WHAT ARE THE DRIVING FACTORS BEHIND THE GROWTH OF THE GLOBAL MARKET FOR SINGLE-USE BIOPROCESSING PROBES AND SENSORS?

The growth of the global market for single-use bioprocessing probes and sensors is driven by factors such as the increasing demand for biopharmaceuticals, the expanding usage of single-use bioreactors, rising investments in the expansion of single-use bioprocessing facilities, and the development of smart single-use sensors.

WHAT ARE THE LATEST TRENDS IN THE GLOBAL MARKET FOR SINGLE-USE BIOPROCESSING PROBES AND SENSORS?

The latest trends in the global market for single-use bioprocessing probes and sensors include a focus on the development of non-invasive single-use sensors and the increasing development of dissolved oxygen single-use sensors.