시장 개관

건선성 관절염 치료제의 글로벌 시장 규모는 2019년 1200억 달러에 이를 것으로 예상된다. 12.46 10억 단위로 2027, 연평균 성장률로 성장 (CAGR) ~의 8.09% USD에서 7.81 10억 2021. Psoriatic arthritis is a chronic inflammatory rheumatic disease characterized by joint pain, stiffness, swelling, erosion, and bone formation. It affects up to 30% of patients with psoriasis, typically those aged between 30 그리고 60 연령. While it often develops about 10 years after psoriasis, some individuals may experience PsA before or without psoriasis. Both men and women can be affected, with women contributing more to the global market due to a higher risk of developing PsA. Estimates suggest that PsA affects over 2 million people in the European Union and around 0.5 million in the United States.

The exact cause of PsA is not yet known, but family history is a significant factor, as approximately 40% of individuals with the disease have a family member affected by psoriasis or arthritis. Risk factors include obesity, severe psoriasis, nail disease, and trauma or deep lesions at trauma sites.

The treatment approach depends on the severity of pain, swelling, and stiffness. Mild cases may only require treatment when joint pain occurs and therapy can be discontinued when symptoms improve. Non-steroidal anti-inflammatory drugs like ibuprofen and naproxen are commonly used as initial treatment. If arthritis does not respond, disease-modifying anti-rheumatic drugs may be prescribed, including sulfasalazine, methotrexate, cyclosporine, and leflunomide. Combinations of these drugs might be used in some cases. Severe forms of PsA may benefit from azathioprine.

Other treatment options include biologics, starting with TNF inhibitors like adalimumab, certolizumab pegol, etanercept, golimumab, and infliximab. Biologics targeting IL-17A inhibitors (secukinumab and ixekizumab), IL-12/23 inhibitor (ustekinumab), IL-23 inhibitors (risankizumab-rzaa and guselkumab), and other classes like abatacept have also demonstrated effectiveness. New oral medications such as tofacitinib, upadacitinib, and apremilast have shown efficacy too.

The psoriatic arthritis treatment market currently includes over 25 assets at various stages of development, with most industry-sponsored drugs in the Phase III stage. Emerging therapies for PsA include Bimekizumab, Tildrakizumab, SHR-0302, Neihulizumab, 무엇보다도. These novel drugs are expected to alter the treatment landscape and offer improved safety and efficacy profiles compared to existing patented commercial drugs.

There are over 150 clinical trials in progress for psoriatic arthritis, with a majority in the Phase III stage. Most trials focus on the late-phase development, ~와 함께 58% in Phase II/III & III and 41% in Phase I-II.

The psoriatic arthritis treatment market utilizes biological therapies such as anti-TNF and anti-interleukin antibodies. 하지만, there is a demand for therapies with novel mechanisms of action (MOAs) that are less immunogenic than current options. New classes of therapies, including interleukin inhibitors, are gaining traction due to improved clinical profiles and convenient dosing.

The recent wave of biologic products for PsA treatment presents lucrative opportunities. Despite the availability of multiple therapies, there is still a need for improvement in the psoriatic arthritis treatment market. The research forecasts the launch of five new agents across eight major markets, including two IL inhibitors (Bimekizumab and Tildrakizumab) and two oral JAK inhibitors (Filgotinib and SHR0302), along with one oral TYK2 inhibitor (Deucravacitinib). The introduction of these late-stage drugs will drive growth in the global market.

Over the past seven years, therapies that target inflammatory pathways beyond TNF have emerged as options for treating PsA. IL-23/IL-17 axis inhibitors have proven to be highly effective, some already in use, while others are in development. Inhibition of IL-23 and IL-17 with monoclonal antibodies has shown significant therapeutic benefits in the psoriatic arthritis treatment market. The research expects a surge of innovation from the research and development pipeline in the next five years, leading to technological advancements that improve interventions and outcomes.

시장 세분화

시장은 다양한 요인에 따라 분류됩니다., including drug class, disease type, gender type, 연령대, severity type, 지리학.

Segmentation by Drug Class
TNF Inhibitors
Interleukin Inhibitors
NSAIDs
Other classes of Drugs

Segmentation by Disease Type
Spondylitis
Enthesitis
Dactylitis

Segmentation by Gender Type
남자들
여성

연령 그룹별 세분화
50 years and Below
50 years and Above

Segmentation by Severity Type
보통의
Mild
Severe

지역별 세분화
북아메리카 – 우리를
유럽 – 독일, 프랑스, 영국, 이탈리아, 스페인
APAC – 중국, 일본

Drug Class: TNF-Alpha inhibitors currently hold a significant share of the global psoriatic arthritis treatment market. 하지만, it is anticipated that interleukin inhibitors will experience the fastest growth during the forecast period. The recent approvals of interleukin inhibitors such as Skyrizi (risankizumab-rzaa) and Cosentyx (Secukinumab) are expected to drive the global psoriatic arthritis treatment market in the coming years.

Gender Type: In the gender type segment, women constitute a notable portion of the global psoriatic arthritis treatment market. This trend can be attributed to the increased risk of psoriatic arthritis among women in recent times.

Disease Type: Enthesitis is projected to hold a significant share of the market. 하지만, Dactylitis is expected to be the fastest growing segment during the forecast period.

연령층: Individuals below the age of 50 are expected to make up a substantial portion of the global psoriatic arthritis treatment market.

Severity Type: Among different severity types, individuals with a mild form of psoriatic arthritis are expected to account for a significant share of the market. 하지만, those with a moderate form are anticipated to be the fastest growing segment in the coming years.

지리적으로, the United States currently dominates the global psoriatic arthritis treatment market. This can be attributed to factors such as healthcare affordability, high levels of knowledge and awareness among the population, and advanced technological capabilities. 그럼에도 불구하고, Germany is expected to exhibit rapid growth, with a high compound annual growth rate (CAGR) in the PsA drug industry. This can be attributed to increased access to and quality of healthcare, greater awareness about disease management, and rising healthcare expenditure in the region. The emergence of biosimilars in markets like China and Japan has the potential to bring about significant changes within their respective psoriatic arthritis therapeutic landscapes.

According to estimates from The research, China had the highest number of prevalent psoriatic arthritis cases in 2020, followed by Spain and the U.K. The growing prevalence of psoriatic arthritis is a key driver for the expansion of the psoriatic arthritis treatment market. ~ 안에 2014, it was estimated that over two million people in the European Union were affected by PsA.

경쟁 구도

The global market for psoriatic arthritis treatment is characterized by the presence of numerous companies offering both generic drugs and patented/commercial drugs for the treatment of PsA. ~ 안에 2013, 미국. Food and Drug Administration (FDA) approved Stelara (Ustekinumab), an interleukin antibody, for the treatment of psoriatic arthritis. More recently, the FDA has approved other interleukins such as Skyrizi (risankizumab-rzaa) ~에 2022 and Cosentyx (secukinumab) ~에 2021 for PsA treatment. While generic products continue to hold a significant share of the psoriatic arthritis treatment market, the introduction of biologics and targeted therapies signals a shift in the therapeutic landscape.

Major players in the global psoriatic arthritis treatment market include AbbVie Inc., 존슨 & 존슨, Takeda Pharmaceutical Co Ltd, Biogen Inc, UCB SA, Amgen, Bristol-Myers Squibb, Pfizer, Eli Lilly and Company, and Novartis. These companies are actively employing growth strategies to strengthen their product portfolios. Such strategies include collaborations and acquisitions, expanding their geographical footprint, investing in research and development, and manufacturing novel drugs to compete in the global market.

Other notable players operating in the psoriatic arthritis treatment market include Sun Pharmaceuticals, Bausch Health Companies Inc, Jiangsu HengRui Medicine Co. (주), Biocad Biopharmaceutical, Meiji Holdings Co Ltd, and Bio-Thera. These players are prioritizing research and development endeavors to develop technologically advanced and innovative psoriatic drugs. 추가적으로, they are entering into collaborations to maintain their position in the industry.

Key companies profiled in this report include AbbVie Inc., 존슨 & 존슨, UCB SA, Amgen, Bristol-Myers Squibb, Pfizer, Eli Lilly and Company, Novartis, Samsung Bioepis, Boehringer Ingelheim, Mylan, 머크 & (주), 주식회사, Coherus BioSciences, 주식회사, Sun Pharmaceuticals, Bausch Health Companies Inc, Jiangsu HengRui Medicine Co. (주), Biocad Biopharmaceutical, Meiji Holdings Co Ltd, Bio-Thera.

주요 질문에 대한 답변

What is the current size of the global psoriatic arthritis treatment market?

The global psoriatic arthritis treatment market is projected to reach a value of USD 12.46 10억 단위로 2027.

What is the growth rate forecasted for the global psoriatic arthritis treatment market?

The global psoriatic arthritis treatment market is expected to grow at a compound annual growth rate (CAGR) ~의 8.09% ~에서 2022 에게 2027.

What are the key drivers of the growth in the psoriatic arthritis treatment market?

Factors such as the increasing adoption of biological therapies, the anticipated launch of emerging drugs, and the focus on developing novel drugs with innovative mechanisms are driving the growth of the market.

Who are the major vendors operating in the psoriatic arthritis treatment market?

AbbVie Inc., 존슨 & 존슨, Takeda Pharmaceutical Co Ltd, Biogen Inc, UCB SA, Amgen, Bristol-Myers Squibb, Pfizer, Eli Lilly and Company, and Novartis are among the leading players in the global psoriatic arthritis treatment market. These companies are implementing various growth strategies to strengthen their product portfolios.

Which region has the largest market share in the global psoriatic arthritis treatment market?

The United States holds the largest share in the global psoriatic arthritis treatment market, primarily due to factors such as healthcare affordability, high level of knowledge and awareness among the population, and technological advancements in the region.